(Photo credit: Erik Williams-Imagn Images)

Masyn Winn and Jose Fermin smacked their first home runs, and the visiting St. Louis Cardinals clinched an interleague series win over the Houston Astros with a 7-5 victory on Saturday.

Alec Burleson also homered for the Cardinals, who pounced on Astros starter Lance McCullers Jr. (1-1) and rode a solid start from right-hander Andre Pallante (2-1), who worked five innings.

The Astros lost their third consecutive game and have dropped 11 of 13.

McCullers labored throughout his five-inning stint. He plunked JJ Wetherholt and Ivan Herrera with pitches to begin his outing and, after walking Jordan Walker to load the bases with one out in the top of the first inning, surrendered a single to Nolan Gorman that plated Wetherholt and Herrera and spotted the Cardinals a 2-0 lead.

McCullers issued walks to Fermin and Wetherholt but stranded both in the second. But with Gorman on first and one out in the third, McCullers grooved a 2-0 sinker that Winn launched into the left-field seats. That 373-foot blast extended the Cardinals' lead to 4-1. McCullers allowed four runs on four hits and three walks with four strikeouts. He threw 91 pitches, 58 for strikes.

Yordan Alvarez crushed his league-leading ninth home run to straightaway center with one out in the bottom of the first. Pallante limited the Astros to that lone tally by working around two baserunners in the second and third innings, and stranding Cam Smith at first in the fourth.

Pallante retired the side in order in the fifth, recording strikeouts of Jose Altuve and Carlos Correa in the frame. He allowed three hits and issued three walks while notching five strikeouts.

The Cardinals tacked on solo runs in the sixth, seventh and eighth innings. Fermin won a 10-pitch battle with Astros left-hander Colton Gordon with his 370-foot shot to left-center that pushed the Cardinals to a 5-1 lead. Burleson led off the seventh with his third homer, a 408-foot blast into the second deck in right field.

Shay Whitcomb slugged a three-run home run off Cardinals reliever George Soriano in the ninth, but closer Riley O'Brien retired Altuve and Alvarez to earn his sixth save.

--Field Level Media